| 1 |  Marc Hirschi (SUI) | Uae Team Emirates | 4:47:15 |
| 2 |  Pavel Sivakov (FRA) | Ineos Grenadiers | 0:02 |
| 3 |  Tadej Pogacar (SLO) | Uae Team Emirates | 0:18 |
| 4 | Guillaume Martin (FRA) | | mt |
| 5 |  Alexey Lutsenko (KAZ) | Astana Qazaqstan Team | mt |
| 6 |  Walter Calzoni (ITA) | Q36.5 Pro Cycling Team | 2:10 |
| 7 |  Richard Antonio Carapaz Montenegro (EQU) | EF Education - Easypost | 2:17 |
| 8 |  Michael Valgren Hundahl (DAN) | | 3:54 |
| 9 |  George Bennett (NZL) | Uae Team Emirates | 4:45 |
| 10 | Mathieu Burgaudeau (FRA) | Totalenergies | 6:04 |
| 11 |  Marcel Camprubi Pijuan (ESP) | Q36.5 Pro Cycling Team | 6:05 |
| 12 | Gianni Moscon (ITA) | Astana Qazaqstan Team | mt |
| 13 | Francesco Busatto (ITA) | Circus - Reuz - Technord | mt |
| 14 |  Felix Großschartner (AUT) | Uae Team Emirates | mt |
| 15 |  Magnus Sheffield (E-U) | Ineos Grenadiers | mt |
| 16 | Filippo Zana (ITA) | Team Jayco Alula | mt |
| 17 | Alexis Vuillermoz (FRA) | Totalenergies | mt |
| 18 | Vincenzo Albanese (ITA) | | mt |
| 19 | Gotzon Martin Sanz (ESP) | | mt |
| 20 | Xabier Berasategi Garmendia (ESP) | | mt |
| 21 | Gianluca Brambilla (ITA) | Q36.5 Pro Cycling Team | mt |
| 22 |  Henok Mulubrhan (ERI) | | mt |
| 23 |  Andrii Ponomar (UKR) | Team Arkéa Samsic | mt |
| 24 | Filippo Magli (ITA) | | mt |
| 25 |  Georg Zimmermann (ALL) | Intermarché - Circus - Wanty | mt |
| 26 | Luca Covili (ITA) | Green Project-Bardiani Csf-Faizanè | mt |
| 27 |  Roberto Carlos González Castillero (PAN) | | 6:13 |
| 28 | Simone Velasco (ITA) | Astana Qazaqstan Team | mt |
| 29 | Alex Martin Gutierrez (ESP) | | mt |
| 30 | Davide Piganzoli (ITA) | | mt |
| 31 |  Harold Alfonso Tejada Canacue (COL) | Astana Qazaqstan Team | mt |
| 32 | Alexandre Balmer (SUI) | Team Jayco Alula | mt |
| 33 | Axel Mariault (FRA) | Cofidis | mt |
| 34 | Ibai Azurmendi Sagastibeltza (ESP) | | mt |
| 35 | Abner Santiago Umba López (COL) | | mt |
| 36 | Enekoitz Azparren Irurzun (ESP) | | 6:17 |
| 37 | Jonathan Lastra Martinez (ESP) | Cofidis | 6:30 |
| 38 | Filippo Fiorelli (ITA) | Green Project-Bardiani Csf-Faizanè | 6:40 |
| 39 |  Ben Swift (G-B) | Ineos Grenadiers | 6:42 |
| 40 | Mattia Bais (ITA) | | 7:26 |
| 41 | Kevin Colleoni (ITA) | Team Jayco Alula | mt |
| 42 | Alessandro De Marchi (ITA) | Team Jayco Alula | 8:08 |
| 43 | Giacomo Garavaglia (ITA) | | 10:52 |
| 44 | Lorenzo Quartucci (ITA) | | mt |
| 45 | Davide Baldaccini (ITA) | | mt |
| 46 | Alejandro Ropero Molina (ESP) | | mt |
| 47 | Jéfferson Armando Ruiz Acuña (COL) | | mt |
| 48 | Emanuele Ansaloni (ITA) | | 10:57 |
| DNF |  Michael Leonard (CAN) | Ineos Grenadiers | - |
| DNF | Brandon Smith Rivera Vargas (COL) | Ineos Grenadiers | - |
| DNF | Ethan Hayter (G-B) | Ineos Grenadiers | - |
| DNF | Ben Tulett (G-B) | Ineos Grenadiers | - |
| DNF | Gleb Brussenskiy (KAZ) | Astana Qazaqstan Team | - |
| DNF | Harold Martin Lopez Granizo (EQU) | | - |
| DNF | Yuriy Natarov (KAZ) | Astana Qazaqstan Team | - |
| DNF | Simon Geschke (ALL) | Cofidis | - |
| DNF | Benjamin Thomas (FRA) | Cofidis | - |
| DNF | Hugo Toumire (FRA) | Cofidis | - |
| DNF | Thomas Champion (FRA) | Cofidis | - |
| DNF | Simon Carr (G-B) | EF Education - Easypost | - |
| DNF | Jefferson Alexander Cepeda Ortiz (EQU) | | - |
| DNF |  Stefan De Bod (AFS) | EF Education - Easypost | - |
| DNF | Mark Padun (UKR) | EF Education - Easypost | - |
| DNF | Lilian Calmejane (FRA) | Intermarché - Circus - Wanty | - |
| DNF | Alexy Faure-Prost (FRA) | | - |
| DNF |  Laurens Huys (BEL) | Intermarché - Circus - Wanty | - |
| DNF | Louis Meintjes (AFS) | | - |
| DNF | Lorenzo Rota (ITA) | Intermarché - Circus - Wanty | - |
| DNF |  Tsgabu Gebremaryam Grmay (ETH) | Team Jayco Alula | - |
| DNF | Jesus David Peña Jimenez (COL) | | - |
| DNF |  Rudy Porter (AUS) | Team Jayco Alula | - |
| DNF |  Sjoerd Bax (P-B) | Uae Team Emirates | - |
| DNF | Jan Christen (SUI) | | - |
| DNF | Davide Formolo (ITA) | Uae Team Emirates | - |
| DNF | Valerio Conti (ITA) | | - |
| DNF |  Veljko Stojnic (SRB) | | - |
| DNF |  German Nicolas Tivani Perez (ARG) | | - |
| DNF | Kirilo Tsarenko (UKR) | | - |
| DNF | Francesco Gavazzi (ITA) | | - |
| DNF | Andrea Garosio (ITA) | | - |
| DNF | Fernando Tercero Lopez (ESP) | | - |
| DNF | Antonio Jesús Soto Guirao (ESP) | | - |
| DNF | Xabier Mikel Azparren Irurzun (ESP) | | - |
| DNF | Peio Goikoetxea Goiogana (ESP) | | - |
| DNF | Luca Cavallo (ITA) | | - |
| DNF | Martin Marcellusi (ITA) | | - |
| DNF | Alessandro Pinarello (ITA) | | - |
| DNF | Matteo Badilatti (SUI) | Q36.5 Pro Cycling Team | - |
| DNF | Alessandro Fedeli (ITA) | Q36.5 Pro Cycling Team | - |
| DNF |  Pavel Novák (RTC) | | - |
| DNF | Jérémy Cabot (FRA) | Totalenergies | - |
| DNF | Valentin Ferron (FRA) | Totalenergies | - |
| DNF | Mattéo Vercher (FRA) | Totalenergies | - |
| DNF | Alessio Cialone (FRA) | | - |
| DNF | Lucas Grolier (FRA) | | - |
| DNF | Alex Molenaar (P-B) | | - |
| DNF | Joan Martí Bennassar Rosselló (ESP) | | - |
| DNF | Jose Luis Faura Asensio (ESP) | | - |
| DNF | Jose Maria Martin Muñoz (ESP) | | - |
| DNF | Mateu Estelrich Cabanellas (ESP) | | - |
| DNF |  Trym Bjørner Westgaard Holther (NOR) | | - |
| DNF | Jonathan Guatibonza (COL) | | - |
| DNF | Andrés Libardo Mancipe (COL) | | - |
| DNF | Alejandro Osorio Carvajal (COL) | | - |
| DNF | Filippo Tagliani (ITA) | | - |
| DNF | Mattia Di Felice (ITA) | | - |
| DNF | Davide Casini (ITA) | | - |
| DNF | Ben Granger (G-B) | | - |
| DNF | Matthew Kingston (G-B) | | - |
| DNF | Edoardo Martinelli (ITA) | | - |
| DNF | Lapo Gavilli (ITA) | | - |
| DNF | Andrea Innocenti (ITA) | | - |
| DNF | Alessandro Monaco (ITA) | | - |
| DNF | Martin Nessler (ITA) | | - |
| DNF | Gabriele Petrelli (ITA) | | - |
| DNF | Matteo Montefiori (ITA) | | - |
| DNF | Andrea Sergiampietri (ITA) | | - |
| DNF | Manuel Capra (ITA) | | - |
| DNF | Nicola Venchiarutti (ITA) | | - |
| DNF | Samuele Mion (ITA) | | - |
| DNF | Lorenzo Ginestra (ITA) | | - |
| DNF |  Kevin Rivera Serrano (CRC) | | - |
| DNF |  Edvard Novak (ROU) | | - |
| DNS |  Lucas Lopes (POR) | | - |
