| 1 |  Andrea Bagioli (ITA) | Soudal - Quick Step | 3:20:25 |
| 2 |  Marc Hirschi (SUI) | Uae Team Emirates | mt |
| 3 |  Alex Aranburu Deba (ESP) | Movistar | mt |
| 4 | Filippo Ganna (ITA) | Ineos Grenadiers | 0:11 |
| 5 |  Rui Alberto Faria da Costa (POR) | Intermarché - Circus - Wanty | mt |
| 6 |  Georg Zimmermann (ALL) | Intermarché - Circus - Wanty | mt |
| 7 | Martin Marcellusi (ITA) | | 0:16 |
| 8 |  Harold Alfonso Tejada Canacue (COL) | Astana Qazaqstan Team | mt |
| 9 | Antonio Tiberi (ITA) | Trek - Segafredo | mt |
| 10 |  Nichola Schultz (AUS) | Israel - Premier Tech | mt |
| 11 |  William Junior Lecerf (BEL) | | mt |
| 12 | Sylvain Moniquet (BEL) | Lotto Dstny | mt |
| 13 |  Simon Yates (G-B) | Team Jayco Alula | mt |
| 14 | Davide Formolo (ITA) | Uae Team Emirates | mt |
| 15 | Florian Lipowitz (ALL) | Bora - Hansgrohe | mt |
| 16 |  Bob Jungels (LUX) | Bora - Hansgrohe | mt |
| 17 | David De La Cruz Melgarejo (ESP) | Astana Qazaqstan Team | mt |
| 18 | Florian Stork (ALL) | Team Dsm | mt |
| 19 |  Jonathan Klever Caicedo Cepeda (EQU) | EF Education - Easypost | mt |
| 20 | Domenico Pozzovivo (ITA) | | mt |
| 21 |  Edward Dunbar (IRL) | Team Jayco Alula | mt |
| 22 |  Amanuel Ghebreigzabhier (ERI) | | mt |
| 23 | Mattia Cattaneo (ITA) | Soudal - Quick Step | mt |
| 24 | Santiago Buitrago Sanchez (COL) | Bahrain Victorious | 0:22 |
| 25 |  Matteo Jorgenson (E-U) | Movistar | 0:29 |
| 26 | Xandro Meurisse (BEL) | Alpecin - Deceuninck | 0:36 |
| 27 | Ben Turner (G-B) | Ineos Grenadiers | 1:24 |
| 28 | Diego Ulissi (ITA) | Uae Team Emirates | 1:29 |
| 29 | Vincenzo Albanese (ITA) | | 1:40 |
| 30 | Jacopo Mosca (ITA) | Trek - Segafredo | 1:43 |
| 31 | Michael Matthews (AUS) | Team Jayco Alula | 2:32 |
| 32 |  Mikkel Frølich Honoré (DAN) | | 2:52 |
| 33 | Stefano Oldani (ITA) | Alpecin - Deceuninck | 2:56 |
| 34 |  Axel Laurance (FRA) | | mt |
| 35 | Sean Flynn (G-B) | Team Dsm | mt |
| 36 | Mathys Rondel (FRA) | | 2:59 |
| 37 | Francesco Busatto (ITA) | Circus - Reuz - Technord | 3:30 |
| 38 | Filippo Baroncini (ITA) | Trek - Segafredo | mt |
| 39 | Diego Pablo Sevilla Lopez (ESP) | | mt |
| 40 | Sébastien Reichenbach (SUI) | Tudor Pro Cycling Team | mt |
| 41 | Giovanni Aleotti (ITA) | Bora - Hansgrohe | mt |
| 42 | Ben Swift (G-B) | Ineos Grenadiers | mt |
| 43 |  Bauke Mollema (P-B) | Trek - Segafredo | mt |
| 44 |  Hermann Pernsteiner (AUT) | Bahrain Victorious | mt |
| 45 | Natnael Tesfatsion Ocbit (ERI) | Trek - Segafredo | mt |
| 46 | Remy Rochas (FRA) | Cofidis | mt |
| 47 | Diego Andres Camargo Pineda (COL) | EF Education - Easypost | mt |
| 48 | Mikel Landa Meana (ESP) | Bahrain Victorious | mt |
| 49 | Iván Ramiro Sosa Cuervo (COL) | Movistar | mt |
| 50 |  Hugo Houle (CAN) | Israel - Premier Tech | 3:37 |
| 51 | Thymen Arensman (P-B) | Ineos Grenadiers | mt |
| 52 | Wout Van Aert (BEL) | Jumbo - Visma | mt |
| 53 | Dries Devenyns (BEL) | Soudal - Quick Step | mt |
| 54 | Wilco Kelderman (P-B) | Jumbo - Visma | mt |
| 55 |  Attila Valter (HON) | Jumbo - Visma | mt |
| 56 | Michael Valgren Hundahl (DAN) | | 4:20 |
| 57 | Brandon Smith Rivera Vargas (COL) | Ineos Grenadiers | 5:09 |
| 58 | Fabio Felline (ITA) | Astana Qazaqstan Team | 5:48 |
| 59 | Cristian Scaroni (ITA) | | mt |
| 60 |  Patrick Bevin (NZL) | Team Dsm | mt |
| 61 | Marcel Camprubi Pijuan (ESP) | Q36.5 Pro Cycling Team | mt |
| 62 | Johannes Adamietz (ALL) | | mt |
| 63 | José Joaquin Rojas Gil (ESP) | Movistar | mt |
| 64 | Romain Combaud (FRA) | Team Dsm | mt |
| 65 | Corbin Strong (NZL) | Israel - Premier Tech | mt |
| 66 | Hugo Toumire (FRA) | Cofidis | mt |
| 67 | Filippo Magli (ITA) | | mt |
| 68 | Kristian Sbaragli (ITA) | Alpecin - Deceuninck | mt |
| 69 | Pieter Serry (BEL) | Soudal - Quick Step | mt |
| 70 | Andrea Piccolo (ITA) | EF Education - Easypost | mt |
| 71 | Frank Van Den Broek (P-B) | | mt |
| 72 | Ivan Garcia Cortina (ESP) | Movistar | mt |
| 73 | Sam Oomen (P-B) | Jumbo - Visma | mt |
| 74 | Salvatore Puccio (ITA) | Ineos Grenadiers | mt |
| 75 | Sean Quinn (E-U) | EF Education - Easypost | mt |
| 76 | Connor Swift (G-B) | Ineos Grenadiers | 5:52 |
| 77 | Anton Palzer (ALL) | Bora - Hansgrohe | 7:11 |
| 78 |  Negasi Haylu Abreha (ETH) | Q36.5 Pro Cycling Team | mt |
| 79 |  Karel Vacek (RTC) | | mt |
| 80 | Filippo Fiorelli (ITA) | Green Project-Bardiani Csf-Faizanè | mt |
| 81 | Matteo Amella (ITA) | | mt |
| 82 | Alex Bogna (AUS) | | 7:15 |
| 83 | Alessandro Tonelli (ITA) | Green Project-Bardiani Csf-Faizanè | mt |
| 84 | Andrea Garosio (ITA) | | mt |
| 85 | Erik Fetter (HON) | | mt |
| 86 |  Rein Taaramäe (EST) | Intermarché - Circus - Wanty | mt |
| 87 | Jesús Herrada Lopez (ESP) | Cofidis | mt |
| 88 | Antoine Debons (SUI) | | mt |
| 89 | Axel Mariault (FRA) | Cofidis | mt |
| 90 | Oier Lazkano Lopez (ESP) | Movistar | 8:54 |
| 91 | Nils Brun (SUI) | | mt |
| 92 | Mathijs Paasschens (P-B) | Lotto Dstny | mt |
| 93 | Simon Geschke (ALL) | Cofidis | mt |
| 94 | Matthew Dinham (AUS) | Team Dsm | mt |
| 95 | Matteo Sobrero (ITA) | Team Jayco Alula | 9:48 |
| 96 | Felix Engelhardt (ALL) | Team Jayco Alula | mt |
| 97 | Marco Frigo (ITA) | Israel - Premier Tech | mt |
| 98 | Alessandro Pinarello (ITA) | | mt |
| 99 | Reto Hollenstein (SUI) | Israel - Premier Tech | mt |
| 100 | Max Kanter (ALL) | Movistar | mt |
| 101 | Nicolo Parisini (ITA) | Q36.5 Pro Cycling Team | mt |
| 102 | Henok Mulubrhan (ERI) | | mt |
| 103 | Nicolo Buratti (ITA) | | mt |
| 104 |  Vegard Stake Laengen (NOR) | Uae Team Emirates | mt |
| 105 | Davide De Cassan (ITA) | | mt |
| 106 | Riccardo Lucca (ITA) | Green Project-Bardiani Csf-Faizanè | mt |
| 107 | Damien Howson (AUS) | Q36.5 Pro Cycling Team | mt |
| 108 | Francesco Gavazzi (ITA) | | mt |
| 109 | Jonas Hvideberg (NOR) | Team Dsm | mt |
| 110 | Steven Kruijswijk (P-B) | Jumbo - Visma | mt |
| 111 | Harrison Wood (G-B) | Cofidis | mt |
| 112 | Maxim Van Gils (BEL) | Lotto Dstny | mt |
| 113 | Lennert Van Eetvelt (BEL) | Lotto Dstny | mt |
| 114 | Gianni Moscon (ITA) | Astana Qazaqstan Team | 9:52 |
| 115 | Jason Osborne (ALL) | Alpecin - Deceuninck | mt |
| 116 | Jimmy Janssens (BEL) | Alpecin - Deceuninck | mt |
| 117 | Edoardo Zambanini (ITA) | Bahrain Victorious | 12:40 |
| 118 | Cees Bol (P-B) | Astana Qazaqstan Team | 14:29 |
| 119 | Julius Van Den Berg (P-B) | | mt |
| 120 | Juan Pedro Lopez Perez (ESP) | Trek - Segafredo | 14:35 |
| 121 | Pavel Novák (RTC) | | mt |
| 122 | Frederik Wandahl (DAN) | Bora - Hansgrohe | mt |
| 123 | Patrick Konrad (AUT) | Bora - Hansgrohe | mt |
| 124 | Dion Smith (NZL) | Intermarché - Circus - Wanty | mt |
| 125 | Sjoerd Bax (P-B) | Uae Team Emirates | mt |
| 126 | Alexander Kamp Egested (DAN) | Tudor Pro Cycling Team | mt |
| 127 | Gianmarco Garofoli (ITA) | Astana Qazaqstan Team | 14:59 |
| 128 | Milan Vader (P-B) | Jumbo - Visma | mt |
| 129 | Jan Maas (P-B) | Team Jayco Alula | mt |
| 130 | Aloïs Charrin (FRA) | | mt |
| 131 |  Jacob Eriksson (SUE) | | mt |
| 132 | Lucas Eriksson (SUE) | Tudor Pro Cycling Team | mt |
| 133 | Charlie Quarterman (G-B) | | 15:02 |
| DNF | Guillaume Martin (FRA) | | - |
| DNF | Andrea Pasqualon (ITA) | Bahrain Victorious | - |
| DNF | Ide Schelling (P-B) | Bora - Hansgrohe | - |
| DNF | Alessandro Iacchi (ITA) | | - |
| DNF | Simone Olivero (ITA) | | - |
| DNF | Alessandro Fancellu (ITA) | | - |
| DNF | Lorenzo Rota (ITA) | Intermarché - Circus - Wanty | - |
| DNF | Madis Mihkels (EST) | Intermarché - Circus - Wanty | - |
| DNF | Gijs Leemreize (P-B) | Jumbo - Visma | - |
| DNF | Mathias Vacek (RTC) | Trek - Segafredo | - |
| DNF | Thomas De Gendt (BEL) | Lotto Dstny | - |
| DNF | Jacopo Guarnieri (ITA) | Lotto Dstny | - |
| DNF | Corey Davis (E-U) | Q36.5 Pro Cycling Team | - |
| DNF |  Kamil Malecki (POL) | Q36.5 Pro Cycling Team | - |
| DNF | Mauro Schmid (SUI) | Soudal - Quick Step | - |
| DNF | Louis Vervaeke (BEL) | Soudal - Quick Step | - |
| DNF | Gregory Lawson Craddock (E-U) | Team Jayco Alula | - |
| DNS | Michael Vink (NZL) | Uae Team Emirates | - |
